Neurology and CNS Clinical Trial Sites Led by Practicing Physicians
Tekton brings practicing physician-investigators, experienced CNS raters, and centralized research support to neurological studies. From migraine and epilepsy to cognitive and neurodegenerative disorders, Tekton sites bring specialized clinical expertise and access to relevant participant populations.
Neurology & CNS Research Capabilities
Experience
Specialized Assessment
- Cognitive and psychometric assessments
- Rater-dependent neurological and CNS endpoints
- Rater training and scale calibration
- Protocol-specific assessment planning
- Device and diagnostic studies
Equipment & Diagnostic Access
Capabilities available at selected sites or through qualified service providers include:
- On-site video electroencephalography (video EEG)
- Access to magnetic resonance imaging (MRI) and computed tomography (CT)
- Access to amyloid and tau positron emission tomography (PET) imaging
- Cerebrospinal fluid collection
- Central and local laboratory support
- Specialty testing and genomic profiling
Featured Neurology, CNS, and Psychiatry Investigators
Ernest Graypel, MD, MHA
Dr. Graypel is a board-certified psychiatrist and CNS Principal Investigator with 20+ years in practice, experienced psychometric raters, and access to patients across mood, anxiety, and cognitive disorders.
Amor Mehta, MD
Dr. Mehta is a dual board-certified neurologist and epileptologist, Principal Investigator, and epilepsy center founder with 15+ years of clinical experience and specialized adult and pediatric epilepsy expertise.
Alex Reish, DO
Dr. Reish is a board-certified osteopathic physician and Principal Investigator with 20+ years focused on headache and chronic pain, a Boulder practice, and Phase 2–4 clinical trial readiness for migraine and pain studies.
Ravi Singareddy, MD
Dr. Singareddy is a board-certified psychiatrist and sleep medicine specialist with 15+ years in practice, 10+ years in research, experience conducting 10+ CNS trials, and psychometric rater experience across mood, anxiety, sleep, and related CNS disorders.
Jeffrey Shenfeld, MD
Dr. Shenfeld is a board-certified internist and Principal Investigator leading a multispecialty CNS and psychiatric research site with multilingual capabilities and access to patients with dementia, mood, anxiety, balance, and vertigo-related conditions.
Andrew H. Martin, MD
Dr. Martin is an adult psychiatrist and child and adolescent psychiatrist with more than 20 years of clinical experience and a longstanding San Antonio practice serving children, adolescents, adults, and families.
Lawrence Ginsberg, MD
Lawrence D. Ginsberg, MD, is a Houston psychiatrist with more than 40 years in clinical practice and Principal Investigator leadership dating to 1992. At Red Oak Psychiatry Associates, Dr. Ginsberg has experience across more than 100 adult and pediatric neuroscience clinical trial protocols involving depression, bipolar disorder, anxiety, post-traumatic stress disorder, attention-deficit/hyperactivity disorder, autism, schizophrenia, and related psychiatric conditions.
His record also includes more than 100 publication and scientific-presentation entries, spanning peer-reviewed articles, abstracts, posters, and continuing medical education monographs. His work covers psychopharmacology, mood disorders, attention-deficit/hyperactivity disorder, autism, and pediatric psychiatry.
Mona Ershadi, MD
Mona Ershadi, MD, is a board-certified adult psychiatrist and Sub-Investigator in Englewood, NJ, with more than 15 years of clinical experience. Her background spans outpatient, inpatient, emergency, and consultation-liaison psychiatry, with expertise across mood, anxiety, psychotic, trauma-related, personality, and neurocognitive disorders. Dr. Ershadi is also a leader on the Tekton Psychiatry Team.
Operational Leaders
Amit Vijapura, MD
Jeffrey Zucker
Brandon Lenfest
Ashley Nagle
The Proven Site Model
The Site Partner Built to Simplify Your Next Neurology Study
A physician-led research model
Neurological studies depend on an understanding of the condition, the participant population, and the demands of the protocol. Tekton combines practicing physicians’ clinical expertise and established relationships with dedicated research staff and centralized operational support.
Paired with dedicated, full-time site staff and a centralized operational infrastructure, this physician-led model improves access to specialized populations and drives stronger enrollment, retention, adherence, and data integrity.
Select best-fit sites
A migraine study and a complex epilepsy protocol require different site capabilities. Tekton evaluates investigator experience, diagnostic resources, rater qualifications, practice populations, and referral pathways to recommend sites suited to the study.
Specialty practices, dedicated research centers, and general medicine sites contribute according to their capabilities and the protocol’s requirements.
Coordinated startup, clear ownership
Tekton coordinates regulatory activities, budgets, contracts, and site preparation to help study teams move from selection through activation.
Days from activation to FPI
Centralized coordination keeps responsibilities visible and helps address readiness gaps before enrollment begins.
Recruitment prioritizing clinical access
Established physician practices, referral relationships, centralized recruitment, and local follow-up support participant identification and engagement.
Tekton's Austin-based recruitment center drives strategy and execution across every site, with accountability underwritten at the site and study level.
Behind these processes sits a database of 340,000+ profiled participants, supplemented by physician referrals, community relationships, and disease-specific group access.
Retention: A Tekton advantage
Clear communication, dependable scheduling, and familiar site teams support continued participation. Neurology study planning also needs to account for caregiver involvement, cognitive or mobility limitations, and the practical demands of repeated assessments.
Tekton's physician relationships and dedicated research teams create a consistent local presence for participants, while centralized oversight helps sites stay aligned with protocol requirements.
That's what has driven an average 95% participant retention rate across Tekton studies (includes general medicine and vaccine studies).
Quality treated as an essential component of delivery
Experienced CNS raters support clinical assessments, scale consistency, and protocol adherence. Rater experience and training needs are evaluated against the study's requirements.
Quality, regulatory, and clinical data teams support site preparation and ongoing execution, including source documentation, data review, and inspection readiness.
Tekton's structure helps identify risk earlier, reinforce consistent processes, and protect participant safety and data integrity throughout your trial. Because Tekton partners with engaged practicing physicians, that alignment holds from the start.
Neurology & CNS Research Questions & Answers
Tekton evaluates studies across depression, anxiety, bipolar disorder, schizophrenia and schizoaffective disorder, post-traumatic stress disorder, obsessive-compulsive disorder, attention-deficit/hyperactivity disorder, substance use disorders, sleep disorders, and related behavioral health indications. Final site recommendations depend on the protocol, investigator experience, participant access, and site readiness.