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Psychiatry Clinical Trial Sites, Led by Practicing Psychiatrists

Bringing top physician-investigator expertise to every Tekton site supporting mental and behavioral health research.

Through centralized guidance, the Tekton Psychiatry Team delivers world-class site performance for mood, anxiety, addiction, and behavioral health studies.

Practicing physician-investigators: Led by practicing physicians who offer extensive access to real patient populations and strategies to recruit and retain the right participants.

Investigator-led protocol review: Feedback on study design, diagnostic requirements, rater needs, and participant access.

Aligned activation: Centralized startup, regulatory, recruitment, and quality across selected Tekton sites.

sites
ready to support psychiatry clinical trials
days
average activation to FPI for CNS studies
+
potential participants in CNS database

Psychiatry Research Capabilities

Experience

  • Addiction and substance use disorders, including alcohol and opioid use disorders
  • Attention-deficit/hyperactivity disorder (ADHD)
  • Anxiety, including generalized and social anxiety disorders
  • Bipolar disorder
  • Depression, including major depressive disorder (MDD) and treatment-resistant depression (TRD)
  • Obsessive-compulsive disorder (OCD)
  • Post-traumatic stress disorder (PTSD)
  • Schizophrenia and schizoaffective disorder in outpatient settings
  • Sleep disorders and insomnia
  • Conditions with psychiatric comorbidities

Specialized Assessment

  • Psychedelic and psychedelic-assisted therapy models
  • Devices and diagnostics
  • Psychometric and rater-dependent assessments

Equipment

  • Purpose-built psychedelic dosing rooms
  • Extended-observation spaces
  • Transcranial magnetic stimulation (TMS) capability
  • Secure Schedule I and II controlled-substance storage
  • On-site video electroencephalography (video EEG)
  • Access to magnetic resonance imaging (MRI), computed tomography (CT), and other imaging services
  • Central and local laboratory and pharmacy support
  • Genomic profiling and additional specialty testing through qualified partners

Tekton Psychiatry Team Leaders

Ernest Graypel, MD, MHA

Dr. Graypel is a board-certified psychiatrist and CNS Principal Investigator with 20+ years in practice, experienced psychometric raters, and access to patients across mood, anxiety, and cognitive disorders.

Ravi Singareddy, MD

Dr. Singareddy is a board-certified psychiatrist and sleep medicine specialist with 15+ years in practice, 10+ years in research, experience conducting 10+ CNS trials, and psychometric rater experience across mood, anxiety, sleep, and related CNS disorders.

Jeffrey Shenfeld, MD

Dr. Shenfeld is a board-certified internist and Principal Investigator leading a multispecialty CNS and psychiatric research site with multilingual capabilities and access to patients with dementia, mood, anxiety, balance, and vertigo-related conditions.

Mona Ershadi, MD

Mona Ershadi, MD, is a board-certified adult psychiatrist and Sub-Investigator in Englewood, NJ, with more than 15 years of clinical experience. Her background spans outpatient, inpatient, emergency, and consultation-liaison psychiatry, with expertise across mood, anxiety, psychotic, trauma-related, personality, and neurocognitive disorders. Dr. Ershadi is also a leader on the Tekton Psychiatry Team.

Operational Leaders

Amit Vijapura, MD - Tekton CNS KOL

Amit Vijapura, MD

Dr. Vijapura is a board-certified psychiatrist and addiction medicine specialist with more than 25 years of clinical research experience across psychiatry, neurology, addiction medicine, and CNS drug development. As Tekton's CNS KOL, Dr. Vijapura provides a comprehensive perspective on both the scientific and site-level execution required for successful psychiatry research.

jeffrey-zucker-headshot

Jeffrey Zucker

Brandon Lenfest

Brandon Lenfest

Ashley Nagle

Ashley Nagle

The Proven Site Model

The Site Partner Built to Simplify Your Next Psychiatry Study

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A physician-led research model

Tekton carefully vets and selects established practicing physicians who bring clinical credibility, therapeutic expertise, and trusted patient relationships to the trials they conduct.

Paired with dedicated, full-time site staff and a centralized operational infrastructure, this physician-led model improves access to specialized populations and drives stronger enrollment, retention, adherence, and data integrity.

Select best-fit sites

Tekton recommends sites based on principal investigator experience, equipment, rater access, referral pathways, existing practice populations, and protocol fit.

Experienced CNS raters support psychometric assessments, scale consistency, rater training, and protocol adherence across participating sites.

Coordinated startup, clear ownership

Tekton centralizes key activities across regulatory, budgets, and site preparation, giving your study team a more consistent path from selection through activation.

Days from activation to FPI

Tekton FPI Timeline July 2025

A single point of coordination surfaces risks earlier, aligns sites around study requirements, and keeps responsibilities visible as the study moves toward FPI.

Recruitment: Activate fast, enroll early

Feasibility, physician databases, centralized recruitment, and site-level follow-up work as one to support your trial.

Tekton's Austin-based recruitment center drives strategy and execution across every site, with accountability underwritten at the site and study level.

Behind these processes sits a database of 340,000+ profiled participants, supplemented by physician referrals, community relationships, and disease-specific group access.

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average enrollment rate
+
profiled database patients

Retention: A Tekton advantage

Retention is shaped by the daily experience of participating in a trial. Clear communication, reliable scheduling, trusted site teams, and thoughtful visit support all influence adherence and continuity.

Tekton's physician relationships and dedicated research teams create a consistent local presence for participants, while centralized oversight helps sites stay aligned with protocol requirements.

That's what has driven an average 95% participant retention rate across Tekton studies (includes general medicine and vaccine studies).

%
participant retention rate

Quality treated as an essential component of delivery

Tekton brings quality assurance, regulatory, clinical data, and risk management into study preparation and ongoing site execution.

Central teams support protocol training, source and electronic data capture review, document management, compliance tracking, corrective action, and inspection readiness.

Tekton's structure helps identify risk earlier, reinforce consistent processes, and protect participant safety and data integrity throughout your trial. Because Tekton partners with engaged practicing physicians, that alignment holds from the start.

Tekton Psychiatry Team Questions & Answers

What psychiatric conditions can Tekton sites support?

Tekton evaluates studies across depression, anxiety, bipolar disorder, schizophrenia and schizoaffective disorder, post-traumatic stress disorder, obsessive-compulsive disorder, attention-deficit/hyperactivity disorder, substance use disorders, sleep disorders, and related behavioral health indications. Final site recommendations depend on the protocol, investigator experience, participant access, and site readiness.

Your Tekton Psychiatry Team Contact

Ashley Nagle

Ashley Nagle

Senior Director, Business Development; Tekton Psychiatry Team Member

Ashley is adept at aligning neurology clinical trials with the right sites and investigators. She serves as a central point of contact for feasibility, site selection, contracting, and study startup.

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