Physician-led. Operationally disciplined. Designed to support the full spectrum of neuropsychiatric and controlled-substance clinical programs—from study start-up through enrollment and beyond.
The right physician. The right team. The right environment. Ready to execute.
Our Capabilities
A CNS research infrastructure built on clinical depth
Tekton's network is purpose-built for the complexity of neuropsychiatric clinical research — combining physician expertise, operational rigor, and purpose-designed facilities.
Physician-Led Sites
Every Tekton site is anchored by a clinically active principal investigator whose patient population aligns directly with the study indication — not a name on a roster, but an engaged physician leader.
Neuropsychiatric Focus
Depression, PTSD, anxiety, sleep disorders, chronic pain, and emerging neurological conditions — our investigator network reflects the full breadth of CNS therapeutic development.
Controlled-Substance Readiness
Dedicated infrastructure for Schedule I/II studies — purpose-prepared dosing environments, extended observation logistics, safety monitoring protocols, and regulatory documentation — built in parallel with investigator onboarding.
"Tekton's model is built to onboard the right physician, build the right team, prepare the right environment, and create sponsor-ready CNS infrastructure — all on a timeline designed for speed, without cutting corners."
— Jeffrey Zucker, Tekton Chief Development Officer and Trained Psychometric Rater
Active clinical populations
Our investigators are practicing clinicians treating depression, PTSD, sleep disorders, chronic pain, and related neuropsychiatric conditions — giving access to the patient populations sponsors need.
Mentorship from within
New investigators receive direct mentorship from experienced Tekton physician leaders — not a training module, but an ongoing relationship that builds research capability and confidence.
Protocol fluency
Our physicians are trained on GCP, protocol-specific requirements, and operational workflows before first patient contact — reducing protocol deviations and sponsor friction.
Consistent execution across sites
Shared training frameworks and Tekton-wide standards create consistency across our network — a meaningful differentiator when sponsors are evaluating multi-site programs.
Site Onboarding: Controlled-Substance
& Psychedelic Program Readiness
From physician identification to PSV-ready infrastructure
Tekton's onboarding model is designed to close the gap between physician interest and true operational readiness — building staffing, space, training, and site processes concurrently rather than sequentially.
Industry context: Benchmark data indicates site activation timelines average 108–150 days, with top-performing sites achieving closer to ~60 days (WCG, 2025). In CNS, added complexity — including rater training, subjective endpoints, and higher screen failure rates — often extends timelines further. Tekton’s parallel-path model is designed to deliver qualified, sponsor-ready CNS sites within a year or less. Once fully onboarded, our sites are built to outperform traditional activation timelines — backed by proven execution in vaccine and cardiometabolic trials with 1.5-day and 5.9-day activation-to-FPI timelines.
Phase 01
Physician Identified
Clinical fit confirmed — patient population, geography, therapeutic alignment, and sponsor-facing credibility evaluated.
Phase 02
Investigator Onboarding & Training
Protocol and GCP training, operational education, and direct mentorship from experienced Tekton physician leaders begins immediately.
Phase 03
Site Leadership In Place
Tekton places experienced site management and coordinator support to drive workflows and provide day-to-day opera
Phase 04
Facility & Dosing Space Prepared
Dosing room design, observation logistics, equipment, comfort elements, and participant flow developed for controlled-substance protocols.
Phase 05
Operational Readiness Built
SOPs, safety processes, regulatory documentation, and sponsor-facing materials aligned. Site assessed for qualification visit readiness.
Phase 06
PSV-Ready Site
Sponsor qualification visit. A credible, organized, execution-ready CNS site — built for the complexity of controlled-substance and neuropsychiatric studies.
"While industry benchmarks show site activation often taking 5–10+ months even at well-resourced independent sites — and considerably longer at academic systems — Tekton's onboarding model is designed to build all essential components in parallel, reducing the gap between physician readiness and sponsor-ready execution."
Why This Matters for Sponsors
Controlled-substance programs require more than investigator interest
They require sites that can translate physician expertise into operational readiness — across training, staffing, facilities, and regulatory preparation. Tekton's parallel-path model is designed to deliver exactly that.
- Physician training and mentorship from Tekton-experienced leaders
- Experienced site staff and local operational leadership
- Purpose-built physical space for long-session CNS protocols
- Aligned SOPs, safety workflows, and sponsor-facing documentation
- A readiness timeline designed for urgency without shortcuts
