Case Study: Achieving 120% of Enrollment Targets for a Teen Cytomegalovirus (CMV) Trial at 5 Sites

Overview

Tekton contributed five clinical research sites to a sponsor-led adolescent CMV vaccine study, each with an enrollment goal of eight participants. Through strategic recruitment, proactive site engagement, and streamlined regulatory operations, Tekton achieved 120% of its enrollment target, enrolling a total of 48 participants in the study.

Key Metrics

%
Average enrollment across 5 sites
Goal: 40 | Enrolled: >48
days
Average regulatory turnaround time across 5 sites

Solutions

Targeted Patient Recruitment

A multi-pronged approach drove the success of this study, tailored to the unique challenges and motivators of the adolescent demographic:

Targeted Digital Campaigns
Tekton partnered with the sponsor to co-fund highly targeted digital ads aimed at parents of teens. These campaigns reached qualified audiences based on geography, age, and interests. This targeted digital campaign not only drove enrollment for the CMV study—it also brought in a large number of pre-screened adolescents who, while not eligible for this trial, have now strengthened Tekton’s database for future teen studies that are often challenging to enroll.

Peer Referrals
Recognizing the influence of peer networks, Tekton encouraged and tracked referrals from already-enrolled participants—a tactic that proved especially effective with this population.

Database Engagement
Tekton’s recruitment team and site staff conducted ongoing outreach via email and SMS to eligible participants within our proprietary databases. At the same time, Principal Investigators and site staff leveraged EMR systems to identify and refer potential participants.

Community Events & Local Visibility
Several sites hosted community outreach events during the recruitment period, with the CMV vaccine study prioritized in signage and staff conversations. Sites also distributed flyers and canvassed local hotspots frequented by teens and parents, including schools, youth centers, and sports facilities.

Accelerated Study Start-Up & Activation

Tekton’s centralized services team leverages a streamlined, proven approach to ensure sites are up and running quickly. With a single point of contact for all site communications, centralized regulatory and IRB coordination, and unified budgeting and contracting processes, sponsors benefit from a fast, predictable, and efficient start-up. Real-time operational dashboards and accurate centralized invoicing keep everything on track and transparent from day one.

Conclusion

Tekton’s integrated approach to recruitment, combined with fast regulatory activation and engaged site teams, helped exceed enrollment targets and support the sponsor’s timeline. This study is a strong example of how Tekton’s infrastructure and local relationships drive results—especially in pediatric and adolescent trials where trust, access, and creativity are essential.

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